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In December 2019, a pandemic of Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus (2019-nCoV), started in the city of Wuhan, capital of Hubei, China.
SARS-CoV-2 is closely related to SARS-CoV-1. Infection is primarily spreadthrough human-to-human transmission via respiratory droplets. Symptoms may range from fever, cough, and breathing difficulties to pneumonia and acute respiratory distress syndrome.

German Robert Koch Institute points out that for early detection of an infection it is advisable to include SARS-CoV-2 / COVID-19 in the differential diagnostic considerations if there is a relevant travel history or signs of viral pneumonia of unclear cause. Samples should be taken in parallel from the upper and lower airways, if possible, and tested.

With immediate effect, Mikrogen GmbH offers a next version of its well-received Multiplex Real-time PCR assay ampliCube Coronavirus Panel on an RUO-Basis (for research use only), soon also as CE-IVD. The assay is able to broadly detect Coronavirus genomic nucleic acids and to differentiate MERS-CoV, SARS-CoV (including new SARS-CoV-2), and seasonal Coronaviruses (CoV-NL63, CoV-OC43, CoV-229E, and CoV-HKU1).
A second SARS-CoV-2 specific confirmatory assay ampliCube Coronavirus SARS-CoV-2 [RUO] and CE-IVD version are in development and will be available soon to confirm SARS-CoV-2.


ampliCube Coronavirus SARS-CoV-2 [RUO] / CE-IVD

  • Save and Fast: Screening and Confirmation in less than 3 hours
  • Screening: Detection of RNA from SARS Coronavirus and SARS-Cov-2 with spezific marker in the E-Gen
  • Confirmation: Detection of RNA from SARS-CoV-2 with specific Marker in Orf1a

  • Art. No.: 50143 for 50 rxn

    • Only for research use [RUO]. Not for use in diagnostic procedures.
    • The CE-IVD version will be available soon

ampliCube Coronavirus Panel [RUO] / CE-IVD


  • Save and Fast: Screeningtest for Corona viruses (including SARS-CoV-2),
    test result in less than 3 hours

  • Detection of RNA from

    • MERS-CoV
    • SARS-Corona viruses (including SARS-CoV-2) with specific marker for   screening in Orf1a
    • Humane seasonal circulating Corona viruses (hCoV NL63, OC43, 229E, HKU1)

  • Ideal shorttest for Respiratory samples: Modular combination with ampliCube PCR-Tests for detection of further viral and bacterial pathogens possible

  • Art. No.: 50142 for 50 rxn

    • Only for research use [RUO]. Not for use in diagnostic procedures
    • The CE-IVD version will be available soon

Use of various real-time PCR cyclers possible

Mic (Magnetic Induction Cycler), Roche LightCycler® 480 Instrument II,
Qiagen Rotor-Gene® Q, Bio-Rad CFX 96, Applied Biosystems
(QuantStudioTM 5 Dx), Stratagene Mx3000P, Applied Biosystems (ABI 7500, ABI 7300)

Information for other PCR cyclers on request


Take advantage of the many benefits of MIKROGEN ampliCube productline


Easy and Modular Handling

  • Complete PCR kits with ready-to-use reagents
  • Uniform cycling program for all pathogens
  • Toolbox System – combination of kits and panels  according to individual needs

 Safe Diagnosis

      • High sensitivity and specificity
      • High safety: internal control for monitoring nucleic acid (RNA/DNA)  extraction and real-time PCR inhibition in each reaction
      • CE label: our PCR tests meet the high standard of the EC directive  98/79/EC on in vitro diagnostic medical device

Flexible and Compatible

  • Validated and Compatible with most common real-time PCR cyclers
    (e.g. Roche LightCycler® 480 II, Qiagen Rotor-Gene® Q, Bio-Rad CFX96, QuantStudioTM 5 Dx, Mic Magnetic Induction Cycler).


  • Space-saving instruments for fast and safe reaction setup and amplification
  • MIKROGEN ampliCube tests can be combined with Myra (Liquid Handling System) and Mic (qPCR Cycler)

Myra - Liquid Handling System                                       Mic - qPCR Cycler




Video | CarL - Complete automation of recomLine strip assays

MIKROGEN Strip Processing

Download "MIKROGEN Strip Processing"-Video:
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  • NEW:
    ampliCube Coronavirus
    Panel detecting COVID-19/SARS-CoV-2

    For more information
    please contact us:

  • Easy, Modular, Safe, Flexible and Compatible
    Convince yourself of our high-quality Multiplex real-time PCR Product Portfolio!

    For more information, please contact us: mikrogen@noSpammikrogen.de

    Mikrogen ampliCube Product Portfolio and complete MDx Workflow
  • NEW: recomDot Borrelia IgG, IgM - ImmunoBlot in 96well plate format

    We are happy to announce the first assay of our new Mikrogen product line recomDot.

    The new protein microarray technology combines the high informative value of immunoblot assays with easy, automated processing on standard ELISA instruments. The test system is perfect for high throuput at low time requirements. 

    recomDot Borrelia IgG, IgM
  • NEW: Mic - Magnetic Induction Cycler for qPCR/Real-time PCRW
    Smart, Small Safe and Accurate - All Mikrogen Real-time PCR Assays are Validated on the Mic.
    For more information, please follow the link
  • Treponema pallidum

    NEW: recomBead Treponema IgG 2.0, IgM 2.0 – Syphilis diagnostics is now part of the Mikrogen bead product portfolio.
    Luminex®-based immunoassay (MagPlex®, magnetic beads) using recombinant antigens for detection of IgG or IgM antibodies against T. pallidum in human serum or plasma.

    recomBead Treponema 2.0 IgG, IgM
innovative through research