recomLine HIV-1 & HIV-2 IgG
Acquired Immunodeficiency Syndrome (AIDS) was described as separate disease pattern in 1981 and the Human immunodeficiency Virus (HIV) was identified as the causative pathogen in 1983. The virus is mainly transmitted through blood or sexual contact.
The greatest challenges in HIV serology are early detection of the infection and reliable detection of all HIV variants. Solving these two problems
- Increases the safety of blood donations and blood products
- Helps to prevent the further spread of HIV infections
- Shortens response times of individual HIV tests after contact (e.g. needle stick injuries)
Because of the serious consequences of a positive result, positive screening tests must be verified using a confirmatory test. The recomLine HIV-1 & HIV-2 IgG test solely uses recombinant antigens based on the ENV, POL and GAG gene segments and allows simple and safe confirmation of HIV screening results.
Product advantages
- Recombinant antigens
- Use of 8 serologically relevant HIV antigens
- Easy and clear interpretation due to easy readable bands
- Determination of the HIV type on a single strip
- Highest specificity - unmatched in comparison with corresponding HIV confirmatory tests
- 100% sensitivity
- Very high seroconversion sensitivity for an early stage diagnosis
- Control band on every strip
- Antibody detection of different subtypes of HIV-1 like group M and group O
- Easy test procedure; automation possible
- Easy and objective evaluation and documentation by recomScan software
- CE label: The recomLine HIV-1 & HIV-2 IgG meets the high standard of the EC directive 98/79/EC on in vitro diagnostic medical devices
Testprinciple and procedure
1st Incubation
A test strip loaded with HIV antigens is incubated with diluted serum or plasma in a dish for 3 hours.
wash 3 times
2nd Incubation
Peroxidase conjugated anti-human antibodies (IgG specific) are added. Incubate for 45 minutes.
wash 3 times
Color reaction
8 minutes after addition of the coloring solution, insoluble colored bands develop at the sites on the test strips occupied by antibodies.
