
recomBead Bordetella pertussis IgG 2.0
recomBead Bordetella pertussis IgA 2.0
Luminex®-based immunoassay (MagPlex®) using recombinant antigens for detection of IgG or IgA antibodies against Bordetella pertussis in human serum or plasma
Bordetella pertussis, which is transmitted by droplet infection, primarily causes the classical clinical presentation of whooping cough with the typical coughing spasms. The clinical symptoms often persist for weeks to months and complications can develop in infants with life-threatening apnoea. Milder progression can be induced by other members of the genus, e.g. Bordetella parapertussis. A preventive vaccine is available.
Along with clinical diagnostics and direct evidence, serology is typically employed about 2–3 weeks after coughing starts. When interpreting the serological results, the immunisation status must always be taken into account because high vaccine induced antibody titres can persist for up to a year. The level of the antibody concentration can contribute to the diagnosis of an acute pertussis infection when considering immunity or an acute infection.
recomBead Bordetella pertussis contains the antigens pertussis toxin (PT) and filamentous haemagglutinin (FHA).
recomBead Bordetella pertussis can be used for clarification/confirmation of screening results or as an initial test for evaluating the infection status using the quantitative anti PT concentration information (IU/ml).
Product advantages
- Meaningful pertussis diagnostics by stating results in international units (IU/ml):
- Easy and safe application:
- Integrated controls in each sample set to check validity criteria (incubation, negative and conjugate controls)
- High and low concentrated controls with target values in IU/ml
- Only one calibrator required per set for recalibration using integrated 4PL WHO standard curves
- High precision and recovery rates when measuring the WHO standard
- Combination of all Mikrogen recomBead 2.0 test systems on one sample plate possible – unique protocol, reagents and test procedure
- Fully automatic processing, software-based analysis and connection to LIMS possible
- Quality guarantee by CE-labelling: the recomBead Bordetella pertussis tests fulfil the high demands of the European Directive 98/79/EC for in vitro diagnostic medical devices.
Commercial product
Article number 5754 | recomBead Bordetella pertussis IgG 2.0 (Reagents for 96 determinations) |
Article number 5755 | recomBead Bordetella pertussis IgA 2.0 (Reagents for 96 determinations) |