Strip-Immunoassay with antigens produced by recombinant techniques for the detection of IgG, IgA and IgM antibodies against Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia psittaci

Chlamydia trachomatis is worldwide one of the most causative agents of sexually transmitted  diseases with an incidence of about 50 million diseases. Besides the urogenital tract, eyes and the respiratory tract of newborns can be infected by Chlamydia trachomatis. The clinical pictures involve primarily urethritis, Trachoma, Lymphogranuloma venereum and can finally cause sterility,  conjunctivitis and reactive arthritis.

The importance of the 1986 identified bacterium Chlamydia pneumoniae is shown by a serological prevalence of about 50%. C. pneumoniae infects mainly the respiratory tract and causes bronchitis, pneumonia and sinusitis amongst others.

Chlamydia psittaci is the causative agent of ornithosis, a rare anthropozoonosis in Germany. Chlamydia psittaci infects usually only persons who have contact to pet birds and farmbirds.

The recomLine Chlamydia is the only test system, which allows the detection of the immune response against all three human pathogenic Chlamydia-species in one step and on one strip. Primarily it has been designed as a confirmatory assay but it can also be applied as a screening assay. The recomLine Chlamydia comprises of different recombinant, species specific antigens sprayed onto nitrocellulose strips so that it is possible to detect IgG, IgA and IgM antibodies against  immunodominant antigens of C. trachomatis, C. pneumoniae and C. psittaci.

Commercial product