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recomBead Borrelia

Luminex®-based immunoassays (MagPlex®) for the detection of IgG or IgM antibodies
against Borrelia burgdorferi sensu lato in human serum, plasma or CSF
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Mikrogen recomBead Borrelia tests are quantitative immunoassays, with recombinantly produced antigens, for the detection of human antibodies against single, diagnostically relevant Borrelia antigens. They allow a flexible combination of the advantages of ELISA and confirmatory testing on one plate. Simultaneous, separate detection of individual antigen-specific antibodies make classification into early and late phase of Borrelia infection possible.

Products

recomBead Borrelia IgG 2.0
Reagents for 96 determinations
 Article no.: 4254 Request

recomBead Borrelia IgM 2.0
Reagents for 96 determinations
 Article no.: 4255 Request

Advantages

  • Use of recombinant Borrelia antigens:

Antigen

Description

Origin
p100 Uncharacterized borrelia-specific antigen B. afzelii
VIsE Vmp (variable major protein) like sequence Expressed, surface lipoprotein Fusion protein, representing the immunodominant VIsE epitopes of different genospecies.
p58 Oligopeptide permease B.garinii
p39 Borrelial membrane protein A (BmpA) B.afzelii
OspA Outer surface protein, Surface protein A B.afzelii
OspC Outer surface protein, Surface protein C B.burgdorferi sensu stricto, B.afzelii, B.garinii
p18 Decorin binding protein A (=DbpA), also called Osp17, Surface protein B.burgdorferi sensu stricto, B.afzelii, B.garinii, B.spielmanii, B.bavariensis
  • Recombinant antigens - minimal cross-reactivity
  • Optimal setting for typing of Borrelia bacteria
  • Possibility of quantitative determination of VlsE exists (research use only)
  • Serum and CSF diagnostics with determination of the borrelia-specific antibody index (AI)
  • Small sample volume (10 μl) is sufficient
  • Ideally suited for high sample throughput
  • Fully automated processing, software-based evaluation (recomQuant) and connection to the laboratory information system possible

Safe and reliable

Validity check by integrated controls (incubation, conjugate and negative control)

Flexible and compatible

Combination of all microgene recomBead immunoassays possible on one plate - uniform processing and interchangeable reagents

High Standard

CE marking: The recomBead Borrelia tests meet the high requirements of the EC Directive 98/79/EC for in vitro diagnostic medical devices