recomBead Borrelia

Luminex®-based immunoassays (MagPlex®) for the detection of IgG or IgM antibodies
against Borrelia burgdorferi sensu lato in human serum, plasma or CSF

Mikrogen recomBead Borrelia tests are quantitative immunoassays, with recombinantly produced antigens, for the detection of human antibodies against single, diagnostically relevant Borrelia antigens. They allow a flexible combination of the advantages of ELISA and confirmatory testing on one plate. Simultaneous, separate detection of individual antigen-specific antibodies make classification into early and late phase of Borrelia infection possible.

 

Please note: Available for sale in Europe only; details available on request.

Products

Reagents for 96 determinations
Article no.: 4254 Request
Reagents for 96 determinations
Article no.: 4255 Request

Advantages

  • Use of recombinant Borrelia antigens:
AntigenDescriptionOrigin
p100Uncharacterized borrelia-specific antigenB. afzelii
VIsEVmp (variable major protein) like sequence Expressed, surface lipoproteinFusion protein, representing the immunodominant VIsE epitopes of different genospecies.
p58Oligopeptide permeaseB.garinii
p39Borrelial membrane protein A (BmpA)B.afzelii
OspAOuter surface protein, Surface protein AB.afzelii
OspCOuter surface protein, Surface protein CB.burgdorferi sensu stricto, B.afzelii, B.garinii
p18Decorin binding protein A (=DbpA), also called Osp17, Surface proteinB.burgdorferi sensu stricto, B.afzelii, B.garinii, B.spielmanii, B.bavariensis
  • Recombinant antigens - minimal cross-reactivity
  • Optimal setting for typing of Borrelia bacteria
  • Possibility of quantitative determination of VlsE exists (research use only)
  • Serum and CSF diagnostics with determination of the borrelia-specific antibody index (AI)
  • Small sample volume (10 μl) is sufficient
  • Ideally suited for high sample throughput
  • Fully automated processing, software-based evaluation (recomQuant) and connection to the laboratory information system possible

Safe and reliable

Validity check by integrated controls (incubation, conjugate and negative control)

Flexible and compatible

Combination of all microgene recomBead immunoassays possible on one plate - uniform processing and interchangeable reagents

High Standard

CE marking: The recomBead Borrelia tests meet the high requirements of the EC Directive 98/79/EC for in vitro diagnostic medical devices