recomLine HEV
Line immunoassays for the detection of IgG or IgM antibodies
against hepatitis E virus (HEV) in human serum and plasma
against hepatitis E virus (HEV) in human serum and plasma
Mikrogen recomLine HEV IgG/IgM tests are serological, qualitative in vitro line immunoassays based on recombinantly produced HEV antigens. The selection of homologous proteins from two different genotypes (genotype 1 and 3) allows high sensitivity even in non-endemic areas with a high proportion of autochthonous hepatitis E cases.
Produkte
Advantages
- Homologous antigens of two genotypes: Genotype 1, Genotype 3
- Highly reliable detection of all four human pathogenic genotypes occurring worldwide
- Can be used as both confirmatory and screening test
- Separate detection of IgG and IgM antibodies
- Easy and clear interpretation due to easy-to-read banding
- Partial and full automation, software-based evaluation (recomScan) and integration with laboratory information system possible
- Highest sensitivity and specificity through the use of recombinant antigens:
| Antigen | Source | Origin |
| O2N | N-terminal part of the ORF* 2 protein (HEV capsid protein) | Genotype 1, Genotype 3 |
| O2M | Middle part of the ORF* 2 protein (HEV capsid protein) | Genotype 1 |
| O2C | C-terminal part of ORF* 2 protein (HEV capsid protein) | Genotype 1, Genotype 3 |
| O3 | HEV ORF* 3 protein | Genotype 1, Genotype 3 |
| *ORF = open reading frame | ||
Safe and reliable
Validity check by integrated, strip-specific cutoff and antibody class controls
Flexible and compatible
Combination of all microgen line immunoassays possible - uniform processing and interchangeable reagents
High Standard
CE mark: The recomLine HEV test meets the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.