recomLine Yersinia

Line immunoassays for the detection of IgG, IgM or IgA antibodies
against Y. enterocolitica and Y. pseudotuberculosis in human serum or plasma

For the Mikrogen recomLine Yersinia assays, the plasmid-encoded virulence proteins (Yersinia Outer Proteins) localized at the cell surface and adhesins for serological species differentiation between Y. enterocolitica and Y. pseudotuberculosis are produced recombinantly. These proteins are expressed only by human pathogenic Yersinia strains.

 

The recomLine Yersinia tests allow the detection of long-standing Yersinia infections and are thus ideally suited to identify Yersinia-induced immunopathological complications and chronic yersinioses. The detection of IgG and IgA antibodies can be an important aid in suspected Yersinia-induced arthritis.

Products

Reagents for 20 determinations
Article no.: 4672 Request
Reagents for 200 determinations
Article no.: 4676 Request
Reagents for 20 determinations
Article no.: 4673 Request
Reagents for 200 determinations
Article no.: 4677 Request

Advantages

  • Detection of all human pathogenic Yersinia by means of Yersinia Outer Proteins (YOPs)
  • Differentiation between Y. enterocolitica and Y. pseudotuberculosis infection serologically possible by using new species-specific Yersinia antigens (PsaA, MyfA)
  • No cross-reactions to Brucella and other pathogens, and no interference by LPS
  • Separate detection of IgG, IgA and IgM antibodies - antibody class control on the test strip - helpful in case of suspected Yersinia-induced arthritis
  • Partial and full automation, software-based evaluation (recomScan) and connection to laboratory information system possible
  • Highest sensitivity and specificity by using different, recombinant Yersinia antigens:
AntigenDescription
YOP MYersinia outer protein
V-AGYersinia virulence factor
PsaAAdhesin (specific for Y. pseudotuberculosis)
YOP DYersinia outer protein
MyfAAdhesin (specific for Y. enterocolitica)
YOP EYersinia outer protein

Safe and reliable

Validity check by integrated, strip-specific cutoff and antibody class controls

Flexible and compatible

Combination of all Mikrogen line immunoassays possible - uniform processing and interchangeable reagents

High Standard

CE mark: The recomLine Yersinia test meets the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.