CLIA Procalcitonin
Procalcitonin (PCT) is a highly specific biomarker for severe bacterial infections and is superior to other inflammatory markers. Under normal conditions, it is produced in thyroid C-cells and is barely detectable in the blood. During bacterial infections, however, it is released by many tissues and rises within 2–4 hours, peaking after 12–24 hours. PCT levels correlate with disease severity, while only very severe non-infectious stimuli cause elevation.
PCT is particularly useful for early detection of sepsis, a life-threatening condition requiring rapid diagnosis. It also supports targeted antibiotic therapy, including initiation, adjustment, and discontinuation. Additionally, PCT helps distinguish bacterial from viral infections, especially in respiratory diseases such as pneumonia or COPD exacerbations, reducing antibiotic use and side effects. It is also valuable in diagnosing bacterial meningitis, pediatric urinary tract infections, and detecting secondary bacterial infections in severe COVID-19 cases.
Products
| Product | Size | Article no. | |
|---|---|---|---|
|
100 Tests
|
Article no.: 71036 | Request |
Advantages
- Sepsis identification and monitoring
- Asses sepsis patient progress and mortality risk
- Signal to start and discontinue of antibiotic treatment in LRTI (Lower Respiratory Tract Infections)
- Differential diagnosis of community-acquired bacterial versus viral pneumonia
- Differential diagnosis of bacterial versus viral meningitis
- The kits are CE-IVD certified and intended for professional use
- For each CLIA kit a corresponding control set is available
| Assay time | 17 min |
| Assay stability | 30 days in-board-stability / in-use-stability until the expiration date at storage temperature 2-8 °C |
| Sample matrix | Serum |
| Sample volume | 34 µL |
| Measuring range | 62.5 - 4000 pg/ml |
| Assay/kit content | Reagent Cartridge with specific reagents for the assay, magnetic particles, calibrators |