recomLine Chlamydia
against Chlamydia trachomatis, Chlamydia pneumoniae and Chlamydia psittaci in human serum or plasma
Mikrogen recomLine Chlamydia tests are serological, qualitative in vitro tests that allow the determination of the immune response of all three human pathogenic Chlamydia species in a single assay. They consist of different species-specific, recombinantly produced antigens on nitrocellulose strips that can be used to determine IgG, IgA and IgM antibodies against immunodominant C. trachomatis, C. pneumoniae and C. psittaci antigens.
The recomLine Chlamydia can be used as a confirmatory test but also as a screening test.
Products
Advantages
- Immune status of a possible C. trachomatis, C. pneumoniae and C. psittaci infection can be confirmed in one preparation and on one strip.
- Helpful for in vitro fertilization diagnostics due to the species-specific antigens MOMP, TARP, CPAF and HSP60 of C. trachomatis
- Highly specific detection of C. pneumoniae due to the use of species-specific antigens among others e.g. YwbM
- Only assay for specific serological C. psittaci diagnostics
- Can be used as both screening and confirmatory assay
- Separate detection of IgG, IgA and IgM antibodies
- Simple and clear interpretation due to easy-to-read banding
- Partial and full automation, software-based evaluation (recomScan) and integration with laboratory information system possible
- Highest sensitivity and specificity through use of recombinant, species-specific antigens:
| Antigen | Species | Signification |
| MOMP | C. tr., C. pn., C. ps. | "major outer membrane protein"; Immunodominant outer membrane antigen |
| OMP2 | C. tr., C. pn., C. ps. | "major outer membrane protein 2"; cysteine-rich outer membrane protein; general marker for infection with Chlamydia |
| TARP | C. tr., C. pn., C. ps. | "translocated actin-recruiting protein"; Binds actin |
| CPAF | C. tr., C. pn., C. ps. | "chlamydial protease-like activity factor"; Viruelance factor |
| HSP60 | C. tr | "heat shock protein 60", Is discussed as an indicator of chronic inflammatory ascending infection (e.g., tubal factor infertility, reactive arthitis), with C. trachomatis |
| YwbM | C. pn | hypothetisches Protein, not present in C. trachomatis and C. psittaci |
Safe and reliable
Validity check by integrated, strip-specific cutoff and antibody class controls
Flexible and compatible
Combination of all microgen line immunoassays possible - uniform processing and interchangeable reagents
High Standard
CE mark: The recomLine Chlamydia tests meet the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.