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recomLine HIV-1 & HIV-2 IgG

Line immunoassay for the detection of IgG antibodies
against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) in human serum or plasma
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Mikrogen recomLine HIV-1 & HIV-2 IgG test is a serological, qualitative in vitro line immunoassay based on recombinant antigens from the ENV, POL and GAG gene regions and enables simple and reliable confirmation of HIV screening results.

 

The major challenges in modern HIV serology are early detection of infection and reliable detection of all HIV variants. Solving these two problems increases the safety of blood donations and blood products, and helps avert the further spread of HIV infection.

Advantages

  • Use of 8 serologically relevant HIV antigens
  • HIV-1 & HIV-2 envelope antigens on one strip for rapid differentiation
  • Very high seroconversion sensitivity for early diagnosis
  • Antibody detection of different subtypes of group M and group O HIV-1
  • Easy and clear interpretation due to easy-to-read banding
  • Partial and full automation, software-based evaluation (recomScan) and integration with laboratory information system possible
  • Highest sensitivity and specificity through the use of recombinant antigens:
Antigen Gene area Function/Localization
gp120 ENV HIV-1 External glycoprotein, component of the viral envelope of HIV-1
gp41 ENV HIV-1 Component of the viral envelope of HIV-1
p51 POL Reverse transcripase of HIV-1
p31 POL Integrase of HIV-1
p24 GAG Capsid protein of HIV-1
p17 GAG Matrix protein of HIV-1
gp105 ENV HIV-2 External glycoprotein, component of the viral envelope of HIV-2
gp36 ENV HIV-2 Transmembrane glycoprotein, component of the viral envelope of HIV-2

Safe and reliable

Validity check by integrated, strip-specific cutoff and antibody class controls

Flexible and compatible

Combination of all microgen line immunoassays possible - uniform processing and interchangeable reagents

High Standard

CE mark: The recomLine HIV-1 & HIV-2 test meets the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.

Products

recomLine HIV-1 & HIV-2 IgG
Reagents for 20 determinations
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