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recomWell Treponema

Enzyme-linked immunosorbent assays (ELISA) for the detection of IgG or IgM antibodies
against Treponema pallidum in serum or plasma
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  6. recomWell Treponema IgG

Mikrogen recomWell Treponema tests are quantitative and qualitative enzyme immunoassays for the detection of IgG and IgM class antibodies to recombinantly produced Treponema antigens.

Products

recomWell Treponema IgG
Reagents for 96 determinations
 Article no.: 5104 Request

recomWell Treponema IgM
Reagents for 96 determinations
 Article no.: 5105 Request

Advantages

  • Highest sensitivity and specificity by using recombinant antigens:

Recombinant  antigen

 recomWell Treponema

Function

Size [kDa]
IgG IgM
TP 47 (1, 2) X X Membrane protein 47
TmpA (1) - X Membrane protein 42
TP 17 (1, 2) X X Membrane protein 17
TP 15 (1, 2) X X Membrane protein 15
1) Norris SJ and the treponema Palidium Polypeptide Research Group polypeptides of Tremponema pallidum: Progress toward Understanding Threir Structural, Functional, and Immunologic Roles. Microbiol. Rev. 1993, 57(3), 750-79
2) Chamberlain NR, Brandt ME, Erwin AL, Radolf, JD and Norgard MV Major integral membrane protein immunogens of Treponema pallidum are proteolipids. Infect. Immun. 1989, 57, 2872-7
3) Atkins DR, Purcell BK, Mitra MM, Norgard MV and Radolf JD Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphilicity. Infect. Immun. 1993, 61, 1202-10
  • Therefore no cross reactions
  • Separate detection of IgG and IgM antibodies
  • No RF absorption necessary for IgM determination
  • Use of single strips possible

Safe and reliable

Fully automatic processing, software-based evaluation and connection to the laboratory information system possible

Flexible and compatible

Combination of all Mikrogen ELISA possible - uniform processing and interchangeable reagents

High Standard

CE mark: The recomWell Treponema tests meet the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.