recomWell Borrelia
Mikrogen recomWell Borrelia tests are qualitative and quantitative enzyme immunoassays for the detection of antibodies against all three Borrelia genospecies (Borrelia burgdorferi sensu stricto, Borrelia garinii, Borrelia afzelii). They are based on recombinantly produced, highly specific and immunodominant Borrelia antigens. It is possible to detect antibodies against all three genospecies in one test run. In addition to the determination of serum antibodies, recomWell Borrelia tests are also ideally suited for the detection of antibodies from the cerebrospinal fluid and thus enable the determination of the Borrelia-specific antibody index from serum and cerebrospinal fluid, an important criterion for neuroborreliosis.
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Advantages
- Highest sensitivity and specificity in early and late phase of infection by using recombinant immunodominant antigens:
IgM: OspC, p41/internal, VlsE (early antigens) and
IgG: p100, OspC, VlsE, p18 (early and late antigens) - Optimal visualization without cross-reacting Borrelia proteins
- Excellent discrimination between negative and positive results
- Separate detection of IgG and IgM antibodies
- No RF absorption necessary for IgM determination
- Standardized serum liquor assay possible - CE certified instructions
- Use of single strips possible
Safe and reliable
Reliable processing through software-based evaluation and connection to the laboratory information system
Flexible and compatible
Combination of all microarray ELISA possible - uniform processing and interchangeable reagents
High Standard
CE mark: The recomWell Borrelia tests meet the high standard of the EC Directive 98/79/EC for in vitro diagnostic medical devices.